I did - my old ST2 had a 14/42 setup and went like a train.
Don't worry about losing top end speed - when was the last time you got it to rev out totally in top?
By this I mean hitting the rev limiter!
In the real world this just does not happen - my ST4S on standard gearing is set for something over 175mph if you could red line it - the real world top end is at least 20mph below.
Change the gearing...if you're that bothered about the cost, a talon front sprocket is only about £14 - buy the altered gearing when you replace the chain & if you don't like it, get a 15 & someone will no doubt have the 14 off you.
Do it.
Go on.
Go on go on go on go on go on go on go on go on