tried one once that you put in the plugholes  turn over the engine put the plugs back in and off you go  it then left a  huge white smokescreen for the next 50 or so miles as the stuff burnt off  not a clue if it worked as it was a  250 superdream and had no performance in the first place 

  i have used injector cleaners in my car to no ill effect  never noticed any difference either in performance or mpg