In my expieriance most Ducati supplied chips/ECU'S that come with exhaust systems are overfuelled,that's a way of making them "safe",ie unlikely to cause the engine to detonate or melt!
So using a PC could sharpen up the throttle response in certain areas(also giving better fuel mileage),but if the PC was fitted by a "muppet",then there's a risk of major problems!
So in my opinion,either have a PC fitted by a very competant person(JHP etc) or leave well alone!
Both my bikes have DP exhausts & chips/ECU'S fitted but no PC,i'm very fussy & have good "feel" when riding,but i've never felt the need to improve what Ducati have supplied!
PS if you were wondering,i'm also reasonably quick, for an old/fat duffer(as a couple of people on this board could second),i use the bikes quite hard & i've never managed to damage the engines on either!